This combination includes three peptides—Tesamorelin, Ipamorelin, and CJC-1295 (without DAC)—each contributing to the stimulation of growth hormone (GH) release through different mechanisms. Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), CJC-1295 is a modified GHRH analogue, and Ipamorelin is a selective ghrelin receptor agonist. Together, they work synergistically to enhance GH secretion and its associated benefits.
Also known as Modified GRF (1-29), CJC-1295 is a synthetic peptide composed of 29 amino acids and is an analogue of growth hormone-releasing hormone (GHRH). It closely resembles natural GHRH, differing by only four amino acid substitutions, but it remains active in the bloodstream for a significantly longer duration. Clinical studies have demonstrated that CJC-1295 effectively increases growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels in humans without serious adverse effects. A 2001 study showed that a 14-day subcutaneous regimen of CJC-1295 was safe and well tolerated.
Ipamorelin is a selective growth hormone secretagogue and a ghrelin receptor agonist. It stimulates growth hormone release with potency comparable to other GHRPs but with fewer appetite-stimulating effects. Unlike many other GH secretagogues, ipamorelin does not significantly increase the secretion of cortisol, acetylcholine, prolactin, or aldosterone, making it the first selective GH secretagogue with this profile.
Tesamorelin is a growth hormone-releasing hormone analogue that raises IGF-1 levels in both men and women by an average of 181 micrograms per liter. It binds and activates human GHRH receptors with potency similar to endogenous GHRH. Besides stimulating growth hormone release, tesamorelin offers additional benefits such as nootropic effects and triglyceride reduction. Recent studies show that it decreases carotid intima-media thickness (CIMT), visceral adipose tissue (VAT), and C-reactive protein (CRP) levels. It does not significantly affect other pituitary hormones. Furthermore, tesamorelin has been shown to improve cognitive function in healthy older adults as well as in individuals with mild cognitive impairment at risk for progressing to Alzheimer’s disease.
The Tesamorelin 20mg + Ipamorelin + CJC-1295 5mg blend is primarily utilized in scientific studies focusing on:
These applications are part of ongoing research aimed at understanding the broader implications of this peptide blend in various biological processes.
This product is intended strictly for laboratory research and is not approved for human consumption.
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