GLOW Wolverine Blend: BPC-157 (10mg) + TB-500 (10mg) + GHK-Cu (50mg)

The GLOW Wolverine Blend is a synergistic combination of three potent peptides—BPC-157, TB-500, and GHK-Cu—each contributing unique regenerative properties:

• BPC-157 (10mg): A synthetic peptide derived from a protective protein found in the stomach lining, known for promoting tissue repair and healing.
• TB-500 (10mg): A synthetic peptide that enhances cell migration and tissue regeneration, playing a key role in wound healing and inflammation reduction.
• GHK-Cu (50mg): A copper-binding peptide that stimulates collagen production, improves skin elasticity, and promotes wound healing, making it a key component for skin rejuvenation and anti-aging benefits.

Together, these peptides work synergistically to accelerate healing, reduce inflammation, and promote overall tissue regeneration

Potential Synergy of BPC-157 and TB-500 in Wound Repair

Research indicates that BPC-157 and TB-500 both stimulate wound healing through different biochemical pathways and may exhibit synergistic effects when combined.

Synergy in Wound Repair

Successful wound healing depends on fibroblasts, which regulate extracellular matrix production, alongside immune cells. For these cells to perform their functions, they must migrate to the injury site—a process heavily reliant on the protein actin. Both BPC-157 and TB-500 play critical roles in actin regulation. BPC-157 increases actin production at the gene level, while TB-500, an actin-binding protein, sequesters actin where it is most effective for filament formation, thereby facilitating cell movement. Together, these peptides synergistically enhance both the quantity and function of actin, accelerating the migration of fibroblasts and immune cells to injured tissues.

The Big Picture

Both TB-500 and BPC-157 interact with growth hormone during the healing process. BPC-157 increases growth hormone receptor expression on fibroblasts, extending their longevity and enhancing their capacity for soft tissue regeneration. TB-500 supports this process by providing fibroblasts with adequate actin stores to utilize their prolonged lifespan effectively. Combining TB-500, BPC-157, collagen, and a growth hormone secretagogue holds promise for significantly increasing wound healing rates, potentially setting a new standard for treatment regimens.

Research Applications

The GLOW Wolverine Blend is primarily utilized in scientific studies focusing on:

• Tissue Repair: Investigating the blend's potential to accelerate the healing of muscles, tendons, ligaments, and other tissues.
• Inflammation Reduction: Exploring its effects on reducing inflammation associated with injuries and chronic conditions.
• Skin Regeneration: Assessing its role in promoting skin health, improving elasticity, and reducing signs of aging.
• Cellular Regeneration: Studying its impact on overall cellular health and regeneration processes.

These applications are part of ongoing research aimed at understanding the broader implications of this peptide blend in various biological processes.

Product Specifications

• Form: Lyophilized (freeze-dried) powder for reconstitution.
• Purity: 99% or higher, ensuring high-quality material for research purposes.
• Packaging: Each package contains 1 vial, each with 70 milligrams of the peptide blend (10mg BPC-157, 10mg TB-500, 50mg GHK-Cu).

This product is intended strictly for laboratory research and is not approved for human consumption.

References

1. C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y.-H. Hsu, and J.-H. S. Pang, “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration,” J. Appl. Physiol., vol. 110, no. 3, pp. 774-780, Oct. [Physiology.org] 
2. J. Kim and Y. Jung, “Potential Role of Thymosin Beta 4 in Liver Fibrosis,” Int. J. Mol. Sci., vol. 16, no. 5, pp. 10624-10635, May 2015. [NCBI] 
3. C.-H. Chang, W.-C. Tsai, Y.-H. Hsu, and J.-H. S. Pang, “Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts,” Mol. Basel Switz., vol. 19, no. 11, pp. 19066-19077, Nov. 2014. [NCBI] 
4. Ran Song, Hyun Choi, Hyung-In Yang, Myung Yoo, Yong-Beom Park, and Kyoung Kim, “Association between serum thymosin B4 levels of rheumatoid arthritis patients and disease activity and response to therapy,” Clinical Rheumatology, vol. 31, pp. 1253-1258, 2012. https://doi.org/10.1007/s10067-012-2011-7 [ResearchGate] 
5. D. Philp et al., “Thymosin B4 Promotes Angiogenesis, Wound Healing, and Hair Follicle Development,” Mechanisms of Ageing and Development, vol. 125, no. 2, pp. 113-115, Feb. 2004, doi:10.1016/mad.2003.11.005. [PubMed]